Tetrahedron

Stereostructure of Rengyol and Isocengyol, Phenylethanoids of Forsythiasuspensa

K Endo, K Seya, H Hikino

Index: Endo, Katsuya; Seya, Kazuhiko; Hikino, Hiroshi Tetrahedron, 1987 , vol. 43, # 12 p. 2681 - 2688

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Citation Number: 31

Abstract

Determination of the stereostructure of rengyol (1), a novel nonaromatic phenylethanoid natural product isolated from Forsythia suspensa, by synthetic means has been described. The Reformatsky reaction of 4-acetoxycyclohexanone with ethyl bromoaoetate afforded two isomeric acetoxy esters (5, 6) and the one (5) which has an equatorial acetoxy1 group yielded on IAH reduction a triol identified as rengyol (1). The isomer (7), obtained similarly ...