Journal of Natural Products 2009-05-22

Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger).

Bing-Hung Chen, Pei-Yu Wu, Kuan-Ming Chen, Tzu-Fun Fu, Hui-Min Wang, Chung-Yi Chen

Index: J. Nat. Prod. 72 , 950-3, (2009)

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Abstract

In the present study on five pure phenolic compounds (1-5) isolated from the rhizomes of Zingiber officinale (ginger) and investigated for their antiallergic potency, rat basophilic leukemia (RBL-2H3) cells were incubated with these compounds and the release of beta-hexosaminidase was measured kinetically. The data obtained suggest that ginger rhizomes harbor potent compounds capable of inhibiting allergic reactions and may be useful for the treatment and prevention of allergic diseases.