Archives of Pharmacal Research
2006-06-01
Synthesis and evaluation of biological properties of benzylideneacetophenone derivatives.
Seikwan Oh, Soyong Jang, Donghyun Kim, Inn-Oc Han, Jae-Chul Jung
Index: Arch. Pharm. Res. 29(6) , 469-75, (2006)
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Abstract
A series of yakuchinone B 1f and its analogs 1a-e was synthesized and evaluated for free radical scavenging, suppression of LPS-induced NO generation, cytotoxicity and anti-excitotoxicity in vitro. Compound 1c exhibited potent anti-excitotoxicity, while all compounds 1a-f showed considerable effects of free radical scavenging, suppression of LPS-induced NO generation, and cytotoxicity in microglia.
Related Compounds
| Structure | Name/CAS No. | Molecular Formula | Articles |
|---|---|---|---|
 |
coniferyl aldehyde
CAS:458-36-6 |
C10H10O3 |
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