Synthesis of nucleotide 5'-diphosphates from 5'-O-tosyl nucleosides

VJ Davisson, DR Davis, VM Dixit…

Index: Journal of Organic Chemistry, , vol. 52, # 9 p. 1794 - 1801

Full Text: HTML

Citation Number: 156

Abstract

... Department of Chemistry, University of Utah, Salt Lake City, Utah 84112 ... This work has produced a large repertoire of synthetic organic and biochemical methods for the phos- phorylation of nuc1eosides.l In general, nucleoside phosphorylation is achieved by nucleophilic ... J. Org ...

 Related Synthetic Route
3'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine Structure

51549-31-6

3'-O-(tert-buty...

~%

5'-TOSYL-2'-DEOXYADENOSINE Structure

6698-29-9

5'-TOSYL-2'-DEO...

Tosyl chloride Structure

98-59-9

Tosyl chloride

~%

5'-TOSYL-2'-DEOXYADENOSINE Structure

6698-29-9

5'-TOSYL-2'-DEO...

N/A Structure

1167433-42-2

N/A

~%

Uridine 5'-diphosphate Structure

58-98-0

Uridine 5'-diph...

Uridine Structure

58-96-8

Uridine

~%

Uridine 5'-diphosphate Structure

58-98-0

Uridine 5'-diph...

2',3'-O-(Methoxymethylene)uridine Structure

16628-81-2

2',3'-O-(Methox...

~%

Uridine 5'-diphosphate Structure

58-98-0

Uridine 5'-diph...

2',3'-O-(methoxymethylene)guanosine Structure

16628-83-4

2',3'-O-(methox...

~%

GDP Structure

146-91-8

GDP

3'-O-(tert-butyldimethylsilyl)-5'-O-(p-toluenesulfonyl)thymidine Structure

129801-99-6

3'-O-(tert-buty...

~%

Thymidine,5'-(4-methylbenzenesulfonate) Structure

7253-19-2

Thymidine,5'-(4...

Tosyl chloride Structure

98-59-9

Tosyl chloride

~%

Thymidine,5'-(4-methylbenzenesulfonate) Structure

7253-19-2

Thymidine,5'-(4...

3'-O-TBDMS-dT Structure

40733-27-5

3'-O-TBDMS-dT

~%

Thymidine,5'-(4-methylbenzenesulfonate) Structure

7253-19-2

Thymidine,5'-(4...

2',3'-O-(methoxymethylidene)-2-N-[(dimethylamino)methylene]guanosine Structure

107202-01-7

2',3'-O-(methox...

~%

GDP Structure

146-91-8

GDP

2',3'-O-(methoxymethylidene)-5'-O-tosyl-2-N-[(dimethylamino)methylene]guanosine Structure

107201-95-6

2',3'-O-(methox...

~%

GDP Structure

146-91-8

GDP

Guanosine Structure

118-00-3

Guanosine

~%

GDP Structure

146-91-8

GDP

2',3'-O-(methoxymethylidene)-4-N-[(dimethylamino)methylene]cytidine Structure

107201-93-4

2',3'-O-(methox...

~%

Cytidine diphosphate Structure

63-38-7

Cytidine diphosphate

2',3'-O-(methoxymethylidene)-5'-O-tosyl-4-N-[(dimethylamino)methylene]cytidine Structure

107201-94-5

2',3'-O-(methox...

~%

Cytidine diphosphate Structure

63-38-7

Cytidine diphosphate

2',3'-O-(methoxymethylidene)cytidine Structure

16628-82-3

2',3'-O-(methox...

~%

Cytidine diphosphate Structure

63-38-7

Cytidine diphosphate

Cytidine Structure

65-46-3

Cytidine

~%

Cytidine diphosphate Structure

63-38-7

Cytidine diphosphate


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