e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Peptide bond formation by aminolysin-A catalysis: a simple approach to enzymatic synthesis of diverse short oligopeptides and biologically active puromycins

H Usuki, Y Yamamoto, J Arima, M Iwabuchi…

Index: Organic and Biomolecular Chemistry, , vol. 9, # 7 p. 2327 - 2335

Full Text: HTML

Citation Number: 10

Abstract

... ichi, Fukuyama-city, Hiroshima 729-3102, Japan e Laboratory of Bioresources Chemistry, The Graduate ... Nevertheless, the chemical methods remain to be developed because of the protection/deprotection ... or byproducts, and the use of excessive amounts of organic solvents. ...

L-leucine Structure

Methyl L-phenylalaninate Structure

Methyl L-phenyl...

~%

H-Phe-Leu-OH Structure

Cyclo(-Phe-Phe) Structure

Cyclo(-Phe-Phe)

N-(4-Nitrophenyl)-L-leucinamide Structure

N-(4-Nitropheny...

~%

H-Phe-Leu-OH Structure

(S)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide Structure

(S)-N-(4-nitrop...

~%

Proline Structure

L-Phenylalanine Structure

L-Phenylalanine

Methyl L-phenylalaninate Structure

Methyl L-phenyl...

~%

H-Phe-Phe-OH Structure

Cyclo(-Phe-Phe) Structure

Cyclo(-Phe-Phe)

ethyl 3-phenyl-L-alaninate Structure

ethyl 3-phenyl-...

~%

(L-F)3-OEt Structure

(L-F)4-OEt Structure

N/A Structure

Detail

H-Phe-PNA HCL Structure

~%

H-Phe-Phe-OH Structure

Cyclo(-Phe-Phe) Structure

Cyclo(-Phe-Phe)

DL-phenylalanine benzyl ester Structure

DL-phenylalanin...

~%

H-D-Phe-D-Phe-OH Structure

H-D-Phe-D-Phe-OH

N/A Structure

L-leucine Structure

L-Methionine, methylester(H-Met-OMe) Structure

L-Methionine, m...

~%

Met-Leu Structure

N-(4-Nitrophenyl)-L-leucinamide Structure

N-(4-Nitropheny...

~%

Met-Leu Structure

N/A Structure

~%

L-Methionine Structure

H-Phe-PNA HCL Structure

~%

L-Phenylalanine Structure

L-Phenylalanine

N-(4-Nitrophenyl)-L-leucinamide Structure

N-(4-Nitropheny...

~%

L-leucine Structure

The steric hindrance of the stepwise reaction of N-carboxy. ...

[Bulletin of the Chemical Society of Japan, , vol. 54, # 9 p. 2705 - 2707]

" Mediator methodology" for the synthesis of peptides in a t...

[Journal of the American Chemical Society, , vol. 107, # 14 p. 4249 - 4252]

Synthesis and conformation of n-trityl dipeptide derivatives

[Tetrahedron, , vol. 40, # 10 p. 1869 - 1872]

Synthesis and conformation of n-trityl dipeptide derivatives

[Tetrahedron, , vol. 40, # 10 p. 1869 - 1872]

Peptidsynthesen über N??Phosphorylaminosäure??phosphorsäure?...

[Chemische Berichte, , vol. 94, p. 2644 - 2655]