e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

The Journal of Organic Chemistry

Cyclodienones. 7. Preparation and reduction of 1-(3, 5-di-tert-butyl-2-hydroxyphenyl) pyridinium halides

G Fukata, T Itoh, M Tashiro

Index: Fukata, Gouki; Itoh, Takashi; Tashiro, Masashi Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4454 - 4458

Full Text: HTML

Citation Number: 5

Abstract

The reactions of &bromo-(la) and 4-chloro-2, 4, 6-tri-tert-butyl-2, 5-cyclohexadien-l-one (lb) with compounds such as pyridine (44, a-(4b), 8-(4c), and y-picoline (4d), and 3, 5-lutidine (48) were carried out under various conditions to produce the corresponding 1-(3, 5-di-tert ...

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~80%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~5%

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4,6-tritert-butyl-4-(2-hydroxyethoxy)cyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

1,2-Bis[(1,3,5-tri-tert-butyl-4-oxo-2,5-cyclohexadien-1-yl)oxy]ethane Structure

1,2-Bis[(1,3,5-...

Detail

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~2%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

Detail

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

Ethylene glycol Structure

Ethylene glycol

~2%

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

Detail

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

Ethylene glycol Structure

Ethylene glycol

~2%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

Pyridine Structure

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~2%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

3-Mepy Structure

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~6%

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4,6-tritert-butyl-4-(2-hydroxyethoxy)cyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~9%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

3-Mepy Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~2%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

Pyridine Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~0%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

Pyridine Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

Ethylene glycol Structure

Ethylene glycol

~0%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

Detail

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~20%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

Pyridine Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~45%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

Pyridine Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

Ethylene glycol Structure

Ethylene glycol

~43%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

Detail

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~41%

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4,6-tritert-butyl-4-(2-hydroxyethoxy)cyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

1,2-Bis[(1,3,5-tri-tert-butyl-4-oxo-2,5-cyclohexadien-1-yl)oxy]ethane Structure

1,2-Bis[(1,3,5-...

Detail

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~10%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

1-(3,5-di-tert-butyl-2-hydroxyphenyl)-4-methylpyridin-1-ium chloride Structure

1-(3,5-di-tert-...

Detail

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

Ethylene glycol Structure

Ethylene glycol

~48%

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

Detail

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

Ethylene glycol Structure

Ethylene glycol

~34%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

3,5-Dimethylpyridine Structure

3,5-Dimethylpyridine

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~37%

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

2,4,6-tritert-butyl-4-(2-hydroxyethoxy)cyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

3-Mepy Structure

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~42%

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

2,4,6-tritert-butyl-4-(2-hydroxyethoxy)cyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

3-Mepy Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~31%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

Pyridine Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~22%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4,6-tritert-butyl-4-hydroxycyclohexa-2,5-dien-1-one Structure

2,4,6-tritert-b...

Detail

3,5-Dimethylpyridine Structure

3,5-Dimethylpyridine

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

~15%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

Detail

4-Picoline Structure

2,5-Cyclohexadien-1-one,4-chloro-2,4,6-tris(1,1-dimethylethyl)- Structure

2,5-Cyclohexadi...

~11%

2,4,6-Tri-tert-butylphenol Structure

2,4,6-Tri-tert-...

2,4-di-tert-butyl-6-chlorophenol Structure

2,4-di-tert-but...

Detail

Pyridine Structure

4-bromo-246-tri-tert-butyl-25-cyclohexadienone Structure

4-bromo-246-tri...

Ethylene glycol Structure

Ethylene glycol

~23%

2,6-Di-tert-butyl-p-benzoquinone Structure

2,6-Di-tert-but...

Detail

Oxidative C–C Bond Cleavage of α??Keto Acids by Cobalt (II) ...

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Silica gel as an effective catalyst for the alkylation of ph...

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A first example of generating aryl cations in the solvolysis...

[Journal of the American Chemical Society, , vol. 107, # 18 p. 5286 - 5288]

Silica gel as an effective catalyst for the alkylation of ph...

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β-Hydroxyalkylation of sterically hindered phenols with epox...

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