Journal of Neurophysiology 2007-03-01

Activity-dependent initiation of a prolonged depolarization in aplysia bag cell neurons: role for a cation channel.

Anne Y Hung, Neil S Magoski

Index: J. Neurophysiol. 97(3) , 2465-79, (2007)

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Abstract

The translation of prior activity into changes in excitability is essential for memory and the initiation of behavior. After brief synaptic input, the bag cell neurons of Aplysia californica undergo a nearly 30-min afterdischarge to release egg-laying hormone. The present study examines a prolonged depolarization in cultured bag cell neurons. A 5-Hz, 10-s action potential train elicited a depolarization of about 10 mV, which lasted