Organic Letters 2009-08-06

Pyridine N-oxides as ligands in Cu-catalyzed N-arylation of imidazoles in water.

Lei Liang, Zhengkai Li, Xiangge Zhou

Index: Org. Lett. 11(15) , 3294-7, (2009)

Full Text: HTML

Abstract

N-arylation of imidazoles with aryl halides catalyzed by a combination of copper(II) sulfate and 1,2-bis(2-pyridyl)-ethane-N,N'-dioxide in water afforded up to 95% yield.