Experientia. Basel 1986-07-15

Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

J E Carrel, J P Doom, J P McCormick

Index: Experientia 42(7) , 853-4, (1986)

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Abstract

Biosynthesis of cantharidin in a blister beetle, Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is attributed specifically to the fluorine substituent. Biochemical inhibition has not been demonstrated previously for an arthropod's defensive substance.