Research communications in chemical pathology and pharmacology 1983-09-01

Prostaglandin B1 can modify the pressor responses to sympathetic nerve stimulation.

N Himori, A M Burkman

Index: Res. Commun. Chem. Pathol. Pharmacol. 41(3) , 397-405, (1983)

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Abstract

PGB1, a metabolite of PGA1, has the ability to enhance peripheral vascular resistance and elevate blood pressure in animals whose vascular tone is low. The effect is not central in origin and apparently is not the result of changes in cholinergic or alpha-adrenoceptor sensitivity or changes in vascular smooth muscle susceptibility per se.