Tetrahedron letters

Efficient synthesis of multi-substituted oxazoles under solvent-free microwave irradiation

JC Lee, HJ Choi, YC Lee

Index: Lee, Jong Chan; Choi, Hyun Jung; Lee, Yong Chan Tetrahedron Letters, 2003 , vol. 44, # 1 p. 123 - 125

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Citation Number: 54

Abstract

A new and efficient method for the synthesis of multi-substituted oxazoles from various carbonyl compounds has been developed using sequential treatment of carbonyl compounds with HDNIB and amides such as acetamide or benzamide under solvent-free microwave irradiation conditions.

~75%

~81%

~95%

~74%

~94%

~70%

~56%

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