Friedel-Crafts acylation with malonic acids in polyphosphoric acid

O Renault, P Dallemagne, S Rault

Index: Renault, Olivier; Dallemagne, Patrick; Rault, Sylvain Organic Preparations and Procedures International, 1999 , vol. 31, # 3 p. 324 - 328

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Citation Number: 5

Abstract

In the course of the synthesis of new heterocyclic derivatives of biological interest,' aryloxopropionic acids 1 were required as potential starting materials for new indanones? cyclopentafuranones3 and cyclopentathiophenones. 4 It is well knowd that malonyl chloride itself or its derivatives condense under the conditions of the Friedel-Crafts reaction with aromatic rings to give such diverse products as monoketones 2, diketones 3 or fused ...