Biochemical and Biophysical Research Communications 2012-05-11

Salvianolic acid A protects human SH-SY5Y neuroblastoma cells against H2O2-induced injury by increasing stress tolerance ability

Heng-ai Zhang, Mei Gao, Li Zhang, Yan Zhao, Li-li Shi, Bai-nian Chen, Yue-hua Wang, Shou-bao Wang, Guan-hua Du, Heng-ai Zhang, Mei Gao, Li Zhang, Yan Zhao, Li-li Shi, Bai-nian Chen, Yue-hua Wang, Shou-bao Wang, Guan-hua Du, Heng-ai Zhang, Mei Gao, Li Zhang, Yan Zhao, Li-li Shi, Bai-nian Chen, Yue-hua Wang, Shou-bao Wang, Guan-hua Du

Index: Biochem. Biophys. Res. Commun. 421(3) , 479-83, (2012)

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Abstract

Highlights ► Sal A inhibits the activation of AMPK. ► Sal A inhibits the activation of Akt. ► The protective effects of Sal A are related to stress tolerance via inhibition of AMPK and Akt.