Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino] benzoxazoles

B Tekiner-Gulbas, O Temiz-Arpaci, I Yildiz…

Index: Tekiner-Gulbas, Betul; Temiz-Arpaci, Ozlem; Yildiz, Ilkay; Altanlar, Nurten European Journal of Medicinal Chemistry, 2007 , vol. 42, # 10 p. 1293 - 1299

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Citation Number: 22

Abstract

Some new 2-(benzyl/p-chlorobenzyl)-5-[(substituted-thienyl/phenyl/phenylthiomethyl/benzyl) carbonylamino] benzoxazole derivatives have been synthesized by reacting 5-amino-2- (benzyl/p-chlorobenzyl) benzoxazoles with appropriate carboxylic acid chlorides. The structures of the synthesized compounds were confirmed by IR, 1H NMR and MASS spectral data. In vitro antimicrobial activities of the compounds were investigated using twofold ...