Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino] benzoxazoles

B Tekiner-Gulbas, O Temiz-Arpaci, I Yildiz…

文献索引：Tekiner-Gulbas, Betul; Temiz-Arpaci, Ozlem; Yildiz, Ilkay; Altanlar, Nurten European Journal of Medicinal Chemistry, 2007 , vol. 42, # 10 p. 1293 - 1299

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被引用次数: 22

摘要

Some new 2-(benzyl/p-chlorobenzyl)-5-[(substituted-thienyl/phenyl/phenylthiomethyl/benzyl) carbonylamino] benzoxazole derivatives have been synthesized by reacting 5-amino-2- (benzyl/p-chlorobenzyl) benzoxazoles with appropriate carboxylic acid chlorides. The structures of the synthesized compounds were confirmed by IR, 1H NMR and MASS spectral data. In vitro antimicrobial activities of the compounds were investigated using twofold ...