Organic Letters 2009-05-07

Inter- and intramolecular photochemical reactions of fleroxacin.

Elisa Fasani, Sandra Monti, Ilse Manet, Fedele Tilocca, Luca Pretali, Mariella Mella, Angelo Albini

Index: Org. Lett. 11(9) , 1875-8, (2009)

Full Text: HTML

Abstract

In the cation formed by photoinduced C-F bond cleavage in fleroxacin, intramolecular reaction with the N-ethyl chain is prevented by the electron-withdrawing effect of fluorine and intermolecular attack by nucleophiles is facilitated.