Life Sciences 2008-01-01

Anxiolytic-like effect of danshensu [(3-(3,4-dihydroxyphenyl)-lactic acid)] in mice

Guyoung Kwon, Hyun Ji Kim, Se Jin Park, Hyung Eun Lee, Hyun Woo, Young Je Ahn, Qingtao Gao, Jae Hoon Cheong, Dae Sik Jang, Jong Hoon Ryu

Index: Life Sci. 101(1-2) , 73-8, (2014)

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Abstract

Aims Danshensu [3-(3,4-dihydroxyphenyl)-lactic acid], a phenylpropanoid compound isolated from Prunella vulgaris var. lilacina, is a well-known antioxidant. Although its antioxidant activity and cardioprotective effect have been reported, the pharmacological properties of danshensu in the central nervous system remain unclear. We investigated whether danshensu exerts anxiolytic-like activity in mice.