Journal of Organic Chemistry 2008-08-15

Copper-mediated N-cyclopropylation of azoles, amides, and sulfonamides by cyclopropylboronic acid.

Sébastien Bénard, Luc Neuville, Jieping Zhu

Index: J. Org. Chem. 73 , 6441, (2008)

Full Text: HTML

Abstract

Reaction of azoles, amides, and sulfonamides in dichloroethane with readily available cyclopropylboronic acid in the presence of copper acetate and sodium carbonate afforded the N-cyclopropyl derivatives in good to excellent yields.