European review for medical and pharmacological sciences 2013-05-01

The effects of L type calcium channels on the electroencephalogram recordings in WAG/RIJ rat model of absence epilepsy.

N Durmus, T Kaya, S G_lt_rk, T Demir, M Parlak, A Altun

Index: Eur. Rev. Med. Pharmacol. Sci. 17(9) , 1149-54, (2013)

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Abstract

Epilepsy is one of the most important central nervous system disorder and 1% of the total world population suffers from this disorder which require a chronic drug treatment. Most of the researchers suggested that excessive calcium entry into neurons is the main triggering event in the initiation of epileptic discharges but the role of L type calcium channels has not been clarified in absence epilepsy.