Patologicheskaia fiziologiia i eksperimental'naia terapiia 2003-01-01

[The lipid peroxidation system in the organism of experimental animals after exposure to cyclic hydrocarbons].

D F Shakirov, D A Enikeev

Index: Patol. Fiziol. Eksp. Ter. (1) , 26-8, (2003)

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Abstract

The paper presents the results of studies of the amounts of diene conjugates, malonic dialdehyde, and Schiff's bases, which are molecular LPO products in the tissues of the lung, liver, kidney in animals exposed to 4-hour inhalation of cyclic hydrocarbons (pyromellitic dianhydride, durol, pseudocumene, and dioxane-1,4). Exposure to ecotoxicants at concentrations of 10 and 1 mg/m3 was found to result in the accumulation of initial, intermediate, and final molecular LPO products. These changes were recorded only after exposure to pseudocumene and dioxane vapors in a dose of 0.1 mg/m3 and after inhalation of dioxane-1,4 vapors in a dose of 0.01 mg/m3.