Tetrahedron

A concise and efficient way to synthesize polyenic diones directly from α, β-unsaturated methyl ketones

M Gao, G Yin, Z Wang, Y Wu, C Guo, Y Pan, A Wu

Index: Gao, Meng; Yin, Guodong; Wang, Zihua; Wu, Yandong; Guo, Cheng; Pan, Yuanjiang; Wu, Anxin Tetrahedron, 2009 , vol. 65, # 31 p. 6047 - 6049

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Citation Number: 19

Abstract

A concise and efficient approach to polyenic compounds containing important diketone structural fragments is developed from readily available α, β-unsaturated methyl ketones in the presence of copper (II) oxide, iodine, and dimethyl sulfoxide. This is a new carbon– carbon double bond-forming reaction from two methyl sp3 C–H bonds and an attractive route to introduce the SMe group into the molecule from inexpensive dimethyl sulfoxide. ...