Palladium??Catalysed Carbonylative α??Arylation of Acetone and Acetophenones to 1, 3??Diketones

…, PG Alsabeh, H Neumann, M Stradiotto…

Index: Schranck, Johannes; Tlili, Anis; Alsabeh, Pamela G.; Neumann, Helfried; Stradiotto, Mark; Beller, Matthias Chemistry - A European Journal, 2013 , vol. 19, # 38 p. 12624 - 12628

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Citation Number: 14

Abstract

The coupling of activated carbon nucleophiles has served as a key platform for the development of palladium-catalysed (hetero) arylation reactions of esters, ketones and related α-CH acidic substrates in the past few decades.[1] Stemming from the pioneering work of Miura, Buchwald, Hartwig and others, catalytic α-arylation procedures have found multiple synthetic applications.[2] Mechanistic studies have led to the development of ...