General Preparation and Controlled Cyclization of Acyclic Terpenoids

J Kuk, BS Kim, H Jung, S Choi, JY Park…

Index: Kuk, Jinchul; Beom, Soo Kim; Jung, Heejung; Choi, Seyoung; Park, Jung-Youl; Koo, Sangho Journal of Organic Chemistry, 2008 , vol. 73, # 5 p. 1991 - 1994

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Citation Number: 8

Abstract

A general preparation method of the all-(E)-polyprenols 12 has been developed from readily available geranyl sulfone by the chain-extension process utilizing the C5 unit 5 and the chain-termination process utilizing the C5 unit 10 together with the chemoselective reductive desulfonylation. The polyprenols 12 were converted to compounds 3 containing two consecutive prenyl sulfone moieties at the tail end, which underwent the controlled ...