Organic Letters 2013-12-20

Conversion of pyridine to imidazo[1,2-a]pyridines by copper-catalyzed aerobic dehydrogenative cyclization with oxime esters.

Huawen Huang, Xiaochen Ji, Xiaodong Tang, Min Zhang, Xianwei Li, Huanfeng Jiang

Index: Org. Lett. 15(24) , 6254-7, (2013)

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Abstract

A rapid and environmentally friendly conversion of pyridine to imidazo[1,2-a]pyridines has been developed via copper-catalyzed aerobic dehydrogenative cyclization with ketone oxime esters.