Molecular Diversity 2011-02-01

Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.

Yogesh Y Pedgaonkar, Mariam S Degani, Radhakrishnan P Iyer

Index: Mol. Divers. 15(1) , 263-7, (2011)

Full Text: HTML

Abstract

With the emergence of high throughput screening of bioactive molecules, there is constant need for the development of new strategies for diversity-oriented synthesis. We describe here a novel one-pot multicomponent reaction for the synthesis of uracil derivatives using easily available starting materials. This new synthetic strategy provides easy access to diverse uracil derivatives in moderate to good yields.