Beating the hydrogen bond: First selective and high-yielding N-acylation process for an α, β-diaminoalcohol

T Storz, P Dittmar, D Grimler, M Testa…

Index: Nishio, Takehiko; Shiwa, Kiyoko Heterocycles, 2004 , vol. 62, p. 313 - 324

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Citation Number: 4

Abstract

... Volume: Page ... Intramolecular hydrogen bonding has been recognized 62 as the dominating noncovalent interaction in 1,2-, 59 1,3-, 60 ... serine esterase model and demonstrated its effectiveness as a nucleophilic catalyst for the hydrolysis of p-nitrophenyl acetate ...