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Beating the hydrogen bond: First selective and high-yielding N-acylation process for an α, β-diaminoalcohol

T Storz, P Dittmar, D Grimler, M Testa…

文献索引:Nishio, Takehiko; Shiwa, Kiyoko Heterocycles, 2004 , vol. 62, p. 313 - 324

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被引用次数: 4

摘要

... Volume: Page ... Intramolecular hydrogen bonding has been recognized 62 as the dominating noncovalent interaction in 1,2-, 59 1,3-, 60 ... serine esterase model and demonstrated its effectiveness as a nucleophilic catalyst for the hydrolysis of p-nitrophenyl acetate ...