Synthesis

Total Synthesis of gem-Difluoromethylenated Analogues of Pironetin

J Lin, X Yue, P Huang, D Cui, FL Qing

Index: Synthesis, , # 2 p. 267 - 275

Full Text: HTML

Citation Number: 5

Abstract

... The other three target gem-difluoromethylenated analogues of pironetin, 1b, 2a, and 2b, were synthesized from 25b, 26a, and 26b ... Scheme 4 Lactone construction and target molecule synthesis. Reagents and conditions: (a) DDQ, CH 2 Cl 2 , H 2 O, 3 h; (b) IBX, EtOAc, reflux, 3 h ...

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