Chemistry: A European Journal 2015-05-26

Smart soft-templating synthesis of hollow mesoporous bioactive glass spheres.

Yunqi Li, Bishnu Prasad Bastakoti, Yusuke Yamauchi

Index: Chemistry 21 , 8038-42, (2015)

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Abstract

Hollow bioactive glass spheres with mesoporous shells were prepared by using dual soft templates, a diblock co-polymer poly(styrene-b-acrylic acid) (PS-b-PAA) and a cationic surfactant cetyltrimethylammonium bromide (CTAB). Hollow mesoporous bioactive glass (HMBG) spheres comprise the large hollow interior with vertical mesochannels in shell, which realize large uptake of drugs and their sustained release. The formation of hydroxyapatite layer on the surface of HMBG particles shows the clear evidence for promising application in bone regeneration. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.