Chemical Communications 2013-04-11

Synthesis of highly substituted oxetanes via [2+2] cycloaddition reactions of allenoates catalyzed by a guanidine Lewis base.

Philipp Selig, Aleksej Turočkin, William Raven

Index: Chem. Commun. (Camb.) 49(28) , 2930-2, (2013)

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Abstract

The first synthesis of highly substituted 3-alkyl-oxetan-2-ylidenes from allenoates was developed by using the bicyclic guanidine 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) as an exceptionally active nitrogen Lewis base catalyst.