Chemico-Biological Interactions 2013-01-01

Molecular and biochemical characterisation of human short-chain dehydrogenase/reductase member 3 (DHRS3)

Tereza Lundová, Lucie Zemanová, Beata Malčeková, Adam Skarka, Hana Štambergová, Jana Havránková, Miroslav Šafr, Vladimír Wsól

Index: Chem. Biol. Interact. 234 , 178-87, (2015)

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Abstract

• DHRS3 is an integral membrane protein with its C-terminus in the cytosol. • Androstenedione and estrone are substrates of DHRS3 in vitro. • DHRS3 was inserted into proteoliposomes. • Expression of DHRS3 protein was detected in the human liver, testes and small intestine.