Base-induced mechanistic variation in palladium-catalyzed carbonylation of aryl iodides

…, J Liu, Z Lü, X Luo, H Zhang, Y Lan…

Index: Hu, Yanhe; Liu, Jing; Lu, Zhixin; Luo, Xiancai; Zhang, Heng; Lan, Yu; Lei, Aiwen Journal of the American Chemical Society, 2010 , vol. 132, # 9 p. 3153 - 3158

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Citation Number: 54

Abstract

A mechanism, which is distinct from the traditional one when sodium alkoxide was used instead of tertiary amines, was proposed for the alkoxycarbonylation of aryl iodides. The catalytic cycle was composed of oxidative addition, subsequent ArPdOR formation, CO insertion to Pd-OR, and final reductive elimination of ArPdCOOR. The kinetic simultaneity of the formation of deiodinated side product from the aryl iodide and aldehyde from ...