Journal of natural products

Semisynthesis of rosmanol and its derivatives. Easy access to abietatriene diterpenes isolated from the genus Salvia with biological activities

JG Marrero, LS Andrés, JG Luis

Index: Marrero, Joaquin G.; Andres, Lucia S.; Luis, Javier G. Journal of Natural Products, 2002 , vol. 65, # 7 p. 986 - 989

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Citation Number: 35

Abstract

The known diterpenes rosmanol (3), rosmaquinone (4), 7-methoxyrosmanol (5), 7- ethoxyrosmanol (6), galdosol (7), and epirosmanol (8) have been obtained by partial synthesis from carnosol (2), an abundant natural product present in Salvia species. The physical and spectroscopic data of these semisynthetic diterpenes were identical to those of authentic natural samples and with data reported in the literature. These abietane ...