High activity of an Fe–tfda (tfda= 2-aminomethyltetrahydrofuran-N, N-diacetic acid) complex for hydroxylation at the aromatic and alkane rings of 2′-deoxyguanosine …

Y Nishida, S Ito

Index: Nishida, Yuzo; Ito, Sayo Journal of the Chemical Society, Chemical Communications, 1995 , # 12 p. 1211 - 1212

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Citation Number: 2

Abstract

An iron (III) complex with tfda (2-aminomethyltetrahydrofuran-N, N-diacetic acid) exhibits high activity for hydroxylation at the 8 and 2′ positions of deoxyguanosine in the presence of hydrogen peroxide; this demonstrates that a facile transformation from deoxyribonucleotide to ribonucleotide in vivo may be possible.