8-hydroxyguanosine

Modify Date: 2025-08-26 00:25:37

8-hydroxyguanosine Structure
8-hydroxyguanosine structure
Common Name 8-hydroxyguanosine
CAS Number 3868-31-3 Molecular Weight 299.240
Density 2.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H13N5O6 Melting Point 232-235ºC
MSDS N/A Flash Point N/A

 Use of 8-hydroxyguanosine


8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.

 Names

Name 8-hydroxyguanosine
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.4±0.1 g/cm3
Melting Point 232-235ºC
Molecular Formula C10H13N5O6
Molecular Weight 299.240
Exact Mass 299.086578
PSA 179.74000
LogP -0.97
Index of Refraction 2.007
InChIKey FPGSEBKFEJEOSA-UHFFFAOYSA-N
SMILES Nc1nc2c([nH]c(=O)n2C2OC(CO)C(O)C2O)c(=O)[nH]1
Storage condition -20°C Freezer

 Synthetic Route

~81%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Lin; Cheng; Ishiguro; Sartorelli Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1194 - 1198

~0%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

~%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Lin; Cheng; Ishiguro; Sartorelli Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1194 - 1198

~66%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

~%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Oklahoma Medical Research Foundation Patent: US4950665 A1, 1990 ;

~%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

~%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301

~%

8-hydroxyguanosine Structure

8-hydroxyguanosine

CAS#:3868-31-3

Literature: Nishida, Yuzo; Ito, Sayo Journal of the Chemical Society, Chemical Communications, 1995 , # 12 p. 1211 - 1212

 Synonyms

8-Hydroxy Guanosine
8-OXO-G
8-OXOGUANOSINE
8-Oxyguanosin
7,8-dihydro-8-oxo-Guanosine
7,8-Dihydroguanosine, 8-oxo-
7,8-dihydro-8-oxo-guanosin
8-OHG
8-oxo-7,8-dihydro-guanosine
8-OH-GUO
8-Hydroxy-guanosin
8-Oxo-7,8-dihydroguanosine
8-Oxo-D-guanosine
8-Oxoguanosin
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