Synthesis and antitumor evaluation of the presumed cytotoxic metabolites of spermine and N, N'-bis (3-aminopropyl) nonane-1, 9-diamine

M Israel, EC Zoll, N Muhammad…

Index: Journal of medicinal chemistry, , vol. 16, # 1 p. 1 - 5

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Citation Number: 44

Abstract

... The ease of addition of H20 and alcohol across the carbonyl groups suggested by this spectral observation actually resulted in a complication in the preparation of 2a .2HC1 for micro- chemical analysis. ... Journal of Medicinal Chemistry, 19 73, Vol. 16, NO. 1 3 ...