Synthesis of naphthyridinone derivatives as potential antimalarials

F Carroll, BD Berrang, CP Linn

Index: Journal of Heterocyclic Chemistry, , vol. 18, # 5 p. 941 - 946

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Citation Number: 5

Abstract

... J. Heterocyclic Chenr.. ... 3 Chemistry Chart 1 outlines the procedure used to prepare 8x4'- -amino- 1 '-methylbutylamino)-5-(~,~trifluoroethoxy)- -1,6 ... of 22 with diethyl ethoxymethylene malonate yielded 23 which could be selectively methylated at the heterocyclic nitrogen. ...