We recently have undertaken in our laboratory a program aiming at designing new anticancer structural families. In the course of this work we have focused more particularly on thiazepine derivatives bearing a sulfonamide group. Consequently numerous compounds, all N-methylated on the sulfonamide moiety were prepared and evaluated in vitro for their antiproliferative activity on the L1210 murine leukemia cell line.[1]1. Leonce , S. , Perez , V. , ...
