Novel dibenzothiazepines without substitution on the sulfonamide group

N Lebegue, N Flouquet, P Berthelot…

文献索引：Lebegue, Nicolas; Flouquet, Nathalie; Berthelot, Pascal; Pfeiffer, Bruno; Renard, Pierre Synthetic Communications, 2002 , vol. 32, # 18 p. 2877 - 2884

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被引用次数: 3

摘要

We recently have undertaken in our laboratory a program aiming at designing new anticancer structural families. In the course of this work we have focused more particularly on thiazepine derivatives bearing a sulfonamide group. Consequently numerous compounds, all N-methylated on the sulfonamide moiety were prepared and evaluated in vitro for their antiproliferative activity on the L1210 murine leukemia cell line.[1]1. Leonce , S. , Perez , V. , ...