Using a convergent synthetic strategy, the synthesis of the previously elusive C4,- symmetrical calix-L4lnaphthalene from 1-naphthol is described. Using other independent convergent routes, syntheses of the other three isomeric calix [4lnaphthalenes originally formed from the direct base-catalyzed condensation of formaldehyde with 1-naphthol are also described. All of these methods involved either a TiC14-or TFA-assisted coupling ...
