e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron: Asymmetry

Biotransformation of organic sulfides. Part 7. Formation of chiral isothiocyanato sulfoxides and related compounds by microbial biotransformation

HL Holland, FM Brown, BG Larsen, M Zabic

Index: Holland, Herbert L.; Brown, Frances M.; Larsen, Brett G.; Zabic, Mirjana Tetrahedron: Asymmetry, 1995 , vol. 6, # 7 p. 1569 - 1574

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Citation Number: 31

Abstract

The fungi Helminthosporium species NRRL 4671 and Mortierella isabellina ATCC 42613 have been used for the biotransformation of a series of isothiocyanatoalkyl methyl sulfides and their synthetic precursors, ω-(methylthio) alkylphthalimides. H. species gave predominantly (S) sulfoxides in all cases; M. isabellina gave (R) isothiocyanatoalkyl methyl sulfoxides, but in the case of two ω-(methylthio) alkylphthalimides substantial conversion ...

N-(6-Bromohexyl)phthalimide Structure

N-(6-Bromohexyl...

~%

6-methylsulfanylhexan-1-amine Structure

6-methylsulfany...

2-(3-(METHYLTHIO)PROPYL)ISOINDOLINE-1,3-DIONE Structure

2-(3-(METHYLTHI...

~%

3-(methylthio)propylamine Structure

3-(methylthio)p...

N-(6-Bromohexyl)phthalimide Structure

N-(6-Bromohexyl...

~%

6-methyl thiohexyl isothiocyanate Structure

6-methyl thiohe...

2-[6-(methylthio)hexyl]-1H-isoindol-1,3(2H)-dione Structure

2-[6-(methylthi...

~%

6-methyl thiohexyl isothiocyanate Structure

6-methyl thiohe...

2-[5-(methylthio)pentyl]-1H-isoindol-1,3(2H)-dione Structure

2-[5-(methylthi...

~%

Berteroin Structure

2-[5-(methylthio)pentyl]-1H-isoindol-1,3(2H)-dione Structure

2-[5-(methylthi...

~%

5-(Methylthio)-1-pentanamine Structure

5-(Methylthio)-...

N-(4-methylsulfanyl-butyl)phthalimide Structure

N-(4-methylsulf...

~%

1-isothiocyanato-4-[(S)-methylsulfinyl]butane Structure

1-isothiocyanat...

4-(METHYLTHIO)-1-BUTYLAMINE Structure

4-(METHYLTHIO)-...

~%

1-isothiocyanato-4-[(S)-methylsulfinyl]butane Structure

1-isothiocyanat...

Total synthesis of the racemic alkaloid diptocarpamine

[Tolstikova, O. V.; Tolstikov, A. G.; Shmakov, V. S.; Galkin, E. G.; Vyrypaev, E. M.; et al. Chemistry of Natural Compounds, 1989 , vol. 25, p. 199 - 202 Khimiya Prirodnykh Soedinenii, 1989 , # 2 p. 232 - 236]

Total synthesis of the racemic alkaloid diptocarpamine

[Tolstikova, O. V.; Tolstikov, A. G.; Shmakov, V. S.; Galkin, E. G.; Vyrypaev, E. M.; et al. Chemistry of Natural Compounds, 1989 , vol. 25, p. 199 - 202 Khimiya Prirodnykh Soedinenii, 1989 , # 2 p. 232 - 236]

Total synthesis of the racemic alkaloid diptocarpamine

[Tolstikova, O. V.; Tolstikov, A. G.; Shmakov, V. S.; Galkin, E. G.; Vyrypaev, E. M.; et al. Chemistry of Natural Compounds, 1989 , vol. 25, p. 199 - 202 Khimiya Prirodnykh Soedinenii, 1989 , # 2 p. 232 - 236]

Total synthesis of the racemic alkaloid diptocarpamine

[Tolstikova, O. V.; Tolstikov, A. G.; Shmakov, V. S.; Galkin, E. G.; Vyrypaev, E. M.; et al. Chemistry of Natural Compounds, 1989 , vol. 25, p. 199 - 202 Khimiya Prirodnykh Soedinenii, 1989 , # 2 p. 232 - 236]

Total synthesis of the racemic alkaloid diptocarpamine

[Tolstikova, O. V.; Tolstikov, A. G.; Shmakov, V. S.; Galkin, E. G.; Vyrypaev, E. M.; et al. Chemistry of Natural Compounds, 1989 , vol. 25, p. 199 - 202 Khimiya Prirodnykh Soedinenii, 1989 , # 2 p. 232 - 236]