Journal of heterocyclic chemistry

Synthesis of 2??(α??hydroxyalkyl)??1, 3??heterocyclic alcohols and aryl carbamates

LN Pridgen, G Miller

Index: Pridgen, Lendon N.; Miller, George Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1223 - 1230

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Citation Number: 27

Abstract

Abstract Several N-(substituted phenyl) carbamoyloxylalkyl-1, 3-heterocycles of the structure 3 were prepared from their respective α-hydroxyalkyl-1, 3-heterocyclic alcohols 1. Efficient syntheses of the prerequisite novel 1, 3-heterocyclic alcohols, such as 2-(α-hydroxyalkyl)-2- oxazolines,− 5, 6-dihydro-1H-1, 3-oxazines,− 1, 4, 5, 6-tetra-hydropyrimidines,-imidazolines, and 4, 5, 6, 7-tetrahydro-1H-1, 3-diazepines were developed. Stannous octoate was found ...