Chemistry–A European Journal

“On Water”, Phosphine??Free Palladium??Catalyzed Room Temperature C H Arylation of Indoles

S Islam, I Larrosa

Index: Islam, Saidul; Larrosa, Igor Chemistry - A European Journal, 2013 , vol. 19, # 45 p. 15093 - 15096

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Abstract

Direct arylation of inert CÀH bonds has received considerable attention in the last few years as an alternative to the classical transition-metal-catalyzed cross-coupling reactions.[1] Direct arylations generally suffer from harsh reaction conditions, such as elevated reaction temperatures, and/or the need for strong oxidants, acids or bases,[2] which can result in functional-group incompatibilities. Further, solvents with undesirable toxicities, such as ...