Rapid synthesis of polyamide dendrimers from unprotected AB2 building blocks

M Okazaki, I Washio, Y Shibasaki…

Index: Okazaki, Masaki; Washio, Isao; Shibasaki, Yuji; Ueda, Mitsuru Journal of the American Chemical Society, 2003 , vol. 125, # 27 p. 8120 - 8121

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Citation Number: 39

Abstract

A rapid synthetic method for the preparation of polyamide dendrimer without protection and deprotection steps has been developed. A symmetrically branched third-generation polyamide dendrimer was prepared by a convergent method involving activation of focal point with a condensing agent, diphenyl (2, 3-dihydro-2-thioxo-3-benzoxazolyl) phosphonate (DBOP), followed by condensation of the active amide with the ...