Advanced Synthesis & Catalysis

(η6??Arene) ruthenium (N??heterocyclic carbene) Complexes for the Chelation??Assisted Arylation and Deuteration of Arylpyridines: Catalytic Studies and Mechanistic …

A Prades, M Poyatos, E Peris

Index: Prades, Amparo; Poyatos, Macarena; Peris, Eduardo Advanced Synthesis and Catalysis, 2010 , vol. 352, # 7 p. 1155 - 1162

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Citation Number: 30

Abstract

Abstract A series of (η 6-arene) ruthenium complexes have been tested in the arylation of arylpyridines. One (η 6-p-cymene) ruthenium (N-heterocyclic carbene) complex (labelled as 1 in the text) was found to be the most effective, being capable of arylating a wide set of substantially different arylpyridines. Complex 1 is also able to promote the regioselective deuteration of a series of arylated N-heterocycles, via a nitrogen-directed mechanism. ...