An Efficient One-Pot Synthesis of 2, 3-dihydroquinazolin-4 (1H)-ones in Green Media

…, A Mobinikhaledi, M Hamidinasab

Index: Fard, Mohammad Ali Bodaghi; Mobinikhaledi, Akbar; Hamidinasab, Mahdia Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2014 , vol. 44, # 4 p. 567 - 571

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Citation Number: 4

Abstract

A series of mono-and disubstituted 2, 3-dihydroquinazoline-4 (1H)-ones have been synthesized in good yields by one-pot reaction using isatoic anhydride, ammonium acetate or amines and aldehydes in green and mild reaction conditions. The effects of various parameters such as the solvent, catalyst amount, reaction time, and temperature were examined. The protocol is simple, efficient, and environmentally benign and the catalyst ...