Chemical Communications

An easy access to fluoroalkanes by deoxygenative hydrofluorination of carbonyl compounds via their tosylhydrazones

AK Yadav, VP Srivastava, LDS Yadav

Index: Yadav, Arvind K.; Srivastava, Vishnu P.; Yadav, Lal Dhar S. Chemical Communications, 2013 , vol. 49, # 21 p. 2154 - 2156

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Citation Number: 14

Abstract

The unique nature of a carbon–fluorine bond often imparts desirable physical, chemical and biological properties with minimal steric interference, 1 thereby playing an intrinsic role in pharmaceuticals, 2,3 agrochemicals, 4 materials 5 and tracers for positron emission tomography (PET). 6 The fluorine atom strategically occurs in approximately 30% of all agrochemicals and 20% of all pharmaceuticals, including drugs such as Cipro, Lipitor, Lexapro and Prozac, ...