Investigation of the stability of the corey-kim intermediate

RD Cink, G Chambournier, H Surjono…

Index: Cink, Russell D.; Chambournier, Gilles; Surjono, Herman; Zhenglong, Xiao; Richter, Steve; Naris, Marius; Bhatia, Ashok V. Organic Process Research and Development, 2007 , vol. 11, # 2 p. 270 - 274

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Citation Number: 10

Abstract

The Corey-Kim oxidation1 of alcohols is an important reaction used by synthetic chemists due to its reliability and the use of inexpensive reagents. Despite the more recent development of alternate oxidation methodologies, such as o-iodoxybenzoic acid (IBX), 2 Dess-Martin periodinane, 3 and tetrapropylammonium perruthenate (TPAP), 4 the Corey- Kim oxidation demonstrates selective reactivity5 that continues to find application in ...