Pelanserin: 3-[3-(4-phenylpiperazin-1-yl) propyl] quinazoline-2, 4 (1H, 3H)-dione

G Aguirre Hernández, R Somanathan…

Index: Garcia; Somanathan; Rivero; Aguirre; Hellberg Synthetic Communications, 2000 , vol. 30, # 15 p. 2707 - 2711

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Abstract

The title compound, C21H24N4O2, is a potent serotonin 5-HT2 and α1-adrenoceptor antagonist. The n-propyl chain links the quinazolinedione heterocycle and the phenylpiperazine group in which the benzene ring is equatorially located and the piperazine