Inhibitory effect of statins on fetal bovine serum??induced proliferation of rat cultured mesangial cells and correlation between their inhibitory effect and transport …

…, T Matsuda, N Ohnishi, T Yokoyama

Index: Nagasawa, Kazuki; Muraki, Yuichi; Matsuda, Tomoko; Ohnishi, Noriaki; Yokoyama, Teruyoshi Journal of Pharmaceutical Sciences, 2000 , vol. 89, # 12 p. 1594 - 1604

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Citation Number: 23

Abstract

Abstract Mesangial cells play an important role in physiologic functions, including the regulation of glomerular filtration, and as a pathogenic factor for proliferative glomerulonephritis. We compared the potencies of the inhibitory effects of simvastatin acid, lovastatin acid, and pravastatin on fetal bovine serum (FBS)-induced proliferation of rat cultured mesangial cells, and examined the correlation between their inhibitory effects ...